Prostate Cancer Research Projects

University of Chicago

Dr. Scott Eggener

“A Study to Evaluate Magnetic Resonance Thermal Image-guided Laser-Induced Thermal Therapy for Pinpoint destruction of Prostate Cancer.”

This human clinical trial, approved by the FDA, will test a treatment that can eliminate prostate cancer cells without damaging the surrounding tissues. The research team will evaluate the feasibility of a FDA-approved thermal therapy and feedback system (Visualase® Thermal Therapy System) for the treatment of biopsy confirmed and MR-imageable prostate lesions. This system has been used in humans for the treatment of brain, spine,thyroid, and liver cancers; however it has not yet been evaluated for the primary treatment of prostate cancer.

This system allows delivery of laser energy while the patient is simultaneously being imaged by an MRI unit. The system’s real-time MR thermal imaging (MRTI) provides information on the thermal dose delivered to the target, resulting in a more precise and controlled delivery which has not been possible with other cancer removal therapies. The researchers hypothesize the system can be a practical and feasible treatment for low-risk localized prostate cancer and allow patients to avoid the complications associated with radical whole-gland therapy. This clinical trial will take up to 2 years. PFC Funding Partners-The Longest Day of Golf Chicago and the University of Chicago Foundation.

New surgical technique uses laser energy to destroy brain tumors

Novel approach is minimally invasive and precise
04:20 PM CDT on Wednesday, October 7, 2009
Wendy Rigby / KENS 5

Perez has had one surgery to remove the tumor, but now the cancer has returned. This time, Dr. John Floyd, a U.T. Health Science Center neurosurgeon, is trying something different.

In an operating room at St. Luke’s Baptist Hospital, the doctor secured an anchor in the outside of the skull. Then, using what’s called neuro-navigation for precision, he slid a catheter several inches inside the head. That catheter houses a laser that can zap the cells growing out of control and threatening Perez’ life.

After the catheter was in place, the patient was moved to an MRI suite, where real-time images showed the doctors the area they were treating.

“Now we have another surgical technique which is minimally invasive and excellent for recurrences,” Floyd said.

While the two-step procedure took several hours, the heating and killing of the tumor took less than five minutes.

“In fighting brain cancer and brain tumors, we need everything that’s available at our disposal to be able to win the battle,” commented Dr. David Jimenez, head of the neurosurgery department at UTHSC.

Full article and video at News5